Congratulations to Asmita and Domenic. Our collaborative work investigating the live single-molecule dynamics of PARP1 and PARP2 with and without DNA damage with Jyothi Mahadevan and Karolin Luger is now published in iScience.
A big congratulations to Sarah and Domenic who finished out the year with excellent BATS presentations, presenting their thesis research for the entire department.
A big congratulations to Sarah and Domenic who recently passed their Biological Engineering Qualifying Exams with flying colors and have now deservedly earned the titles of PhD candidates - Congrats Sarah & Domenic!
Congratulations to Viraat and Harvey for receiving graduate fellowships.
We are thrilled to share our new preprint Region Capture Micro-C reveals coalescence of enhancers and promoters into nested microcompartments. We develop a new chromosome conformation capture method that we call Region Capture Micro-C (RCMC). With RCMC we generate the deepest 3D genome maps thus far and reveal new insights into the mechanisms of enhancer-promoter and promoter-promoter interactions. These interactions can be seen as "dots" in the contact maps below: Please read the preprint for the full story. And huge congratulations to Viraat and Miles for putting this together.
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March 2024
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