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Congrats to Viraat: New preprint with Aryee, Johnstone, Eyler, Wood labs and more

9/23/2023

 
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Congratulations to Viraat on a new collaborative preprint with Christian Cerda-Smith, Haley Hutchinson et al. where Viraat's Region Capture Micro-C was applied together with CRSPRa screens to identify functional enhancers for the tumor suppressor PTEN which is now on BioRxiv, revealing a separation between long-range structural and activating elements.

Additionally, congrats to Viraat for winning the Wishnok prize (for the second time!) and for being named a Siebel Scholar.
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Welcome Sumin

8/22/2023

 
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We are thrilled to welcome Sumin Kim to the lab as a new post-doc.

Sumin received her undergraduate degree from MIT before doing a PhD at Michigan, where she studied TorsinA, which you can read more about in Kim et al. TorsinA is essential for the timing and localization of neuronal nuclear pore complex biogenesis, 2023.

Welcome back to MIT, Sumin!

Lab potluck

7/24/2023

 
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The 4D Nucleome review paper is out

7/24/2023

 
The 4D Nucleome review is out. It surveys recent advances in our understanding of the 4D Nucleome (3D space + time) with a focus on techniques and methods used to study it. Read the full review here.
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Farewell to Shdema

6/19/2023

 
We said goodbye to Shdema who is heading back to Israel for her next adventure. Shdema has been heading a project to understand enhancer dysregulation in cancer and we wish her all the best for her new adventure. We celebrated Shdema by cooking a spring meal together at the Cambridge School of Culinary Arts.
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Summer build-a-fluorescence-microscope bootcamp

6/18/2023

 
Thanks to Domenic for teaching the summer build-a-fluorescence-microscope bootcamp again this year, covering both the theory of optics and microscopy and guiding everyone through building their own fluorescence microscope.
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Welcome Angelina

6/9/2023

 
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We are thrilled to welcome Angelina Schorr to the lab, who joins us from Brown University and who will be working with us this summer as part of MIT's Summer Research Program (MSRP).

Angelina will be working with Sarah on understanding bidirectional promoters.

Annual photoshoot

6/9/2023

 
We had our annual photoshoot by resident expert photographer, Michele!
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Congrats to Viraat and Miles on the publication of their Region Capture Micro-C paper

5/8/2023

 
Congratulations to Viraat and Miles on their Region-Capture Micro-C (RCMC) paper being published in Nature Genetics today - you can read the full story here.

By combining region capture with Micro-C, RCMC is able to resolve 3D genome structure at unprecedented depth and helped us uncover new features of the 3D genome.

See also a news story from MIT News by Anne Trafton and a nice 2-min video explainer featuring Viraat and Miles by Melanie Gonick.
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Celebrating Harvey's paper and saying goodbye to Luoyu

5/6/2023

 
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