Congratulations to Harvey on the publication of his new review article in Nature Reviews Molecular Cell Biology, which can be found here.
We went to a Celtics game and celebrated!
Good news this week:
We got a new "Bridge Grant" with Zuzana Tothova (Dana-Farber) to study the effect of loss of function mutations in cohesin that cause cancer.
Also Anders has a new title: Associate Professor.
We are thrilled to welcome 3 new lab members:
Allison Vieira has just joined the lab as a tech associate and will be managing the lab and working to understand genome structure and function.
Michael Quezada is a Harvard-MIT MD-PhD graduate student working jointly with Jason Buenrostro and working on understanding the selectivity of intrinsically disordered regions at scale
Varshini Ramanathan is a BE graduate student and will work on loops, bioinformatically finding them and watching them form as cells respond to their environment.
Welcome Allison, Michael, and Varshini!
Congratulations to Christos and Domenic: New preprint with Jane Skok's lab to understand cancer-associated CTCF mutations
CTCF is frequently mutated in cancer and in neurodevelopmental disorders: Jane Skok's lab used an inducible genetic complementation system to study the effects on these mutations on transcription and genome organization, and Christos and Domenic contributed excellent FRAP analyses to understand how these mutations affect CTCF's dynamics, residence time, and bound fraction.
See the full preprint on BioRxiv.