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  • Main
  • Team
  • Research
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  • Join
  • Values
  • Data
  • Code
  • Reagents
  • Contact

Socially distant lab outing

8/21/2020

 
After months of virtual get-togethers, the Hansen lab gathered for a socially distant summer outing on the banks of the Charles. With stomachs full of Thai food, we spent the warm Boston evening chatting and trying to find the "spies" in the game of Resistance. With our first outing since March a resounding success, the Hansen lab is ready to take on the Fall semester!
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2 new review papers from the lab

8/10/2020

 
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We contributed to two new review papers.

In one we reviewed new chromatin technologies that are shining a new light on how chromatin and chromosomes work inside of cells. Find Advances in Chromatin and Chromosome Research: Perspectives from Multiple Fields in Molecular Cell.

In the other, we review how CTCF and cohesin might interact and how this may regulate chromatin looping in cells. Find
CTCF as a boundary factor for cohesin-mediated loop extrusion: evidence for a multi-step mechanism in Nucleus.

Big week for the lab: Asmita has started and Harvey was awarded a fellowship

6/24/2020

 
It has been a big week for the lab and we are happy to finally return to lab.

We are thrilled to welcome Asmita to the lab. Asmita started as a Technical Associate on Monday of this week and we are very excited about her joining the team. She has already started culturing cells and doing some imaging.

And Harvey was the 2020-2021 MathWorks Engineering Fellowship. MathWorks is the company behind MATLAB and is supporting Harvey's computational work for the next year. A big congratulations to Harvey and thank you to MathWorks.

Shdema is a Zuckerman STEM Scholar

5/6/2020

 
Congratulations to Shdema on being awarded a post-doctoral fellowship through the Zuckerman STEM Leadership Program for the academic year of 2020-2021. We look forward to Shdema joining us in August. Here is the full announcement.

Congratulations to Viraat, Michele, and Denise

4/9/2020

 
In these uncertain times, it is especially nice to receive good news.

Viraat received honorable mention for his NSF Graduate Research Fellowship Program (GFRP) application. He can be found here. Congratulations to Viraat!

Michele received a post-doctoral fellowship "award without funding" from the Autism Science Foundation. Due to COVID-19 they are not currently providing funded awards, but the "project was considered to be so meritorious that it would have received funding". Congratulations to Michele!

Denise is celebrating 30 years with MIT today. What a milestone. Congratulations to Denise!

The high-resolution Micro-C paper is published

3/25/2020

 
The ultra-high resolution Micro-C paper in mouse embryonic stem cells is published in Molecular Cell. Besides capturing Compartments, TADs, Loops, Stripes/Flames, Micro-C is uniquely capable of capturing transcription-associated chromatin interactions such as Enhancer-Promoter (E-P) and Promoter-Promoter (P-P) interactions.
This paper was led by Stanley Tsung-Han Hsieh and please read the full story here. A complementary Micro-C paper back-to-back can be found here.
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Lab donation to help fight COVID-19

3/25/2020

 
We are proud to be donating 57,000 nitrile gloves to local Cambridge/Boston area hospitals!
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lab trip to Bota Borg

3/12/2020

 
Firm believers in the importance of collegiality, the Hansen lab decided to inaugurate its first lab outing by trading the lab bench for Boston's Boda Borg. After an evening of jumping around, solving puzzles, and learning from our mistakes, we triumphantly completed 3 rooms and returned home. Who knows where we'll head to next...
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Asmita Jha will join the lab as our new Technical Associate

3/12/2020

 
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We are incredibly excited that Asmita Jha will join us as a Technical Associate this June 2020.

Asmita will join us from the University of Colorado, Boulder where she has been studying Molecular and Cellular Developmental Biology and working with Karolin Luger on using live-cell imaging to understand DNA damage dynamics.

We look forward to welcoming Asmita!

Two new protocols published: Convenient absolute protein abundance quantification and robust co-IPs

2/22/2020

 
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Two new protocols led by Claudia Cattoglio are now published with detailed step-by-step guidelines.
The first provides a detailed protocol for how to measure the absolute abundance (#proteins per cell) of any Halo-Tagged protein in a couple of afternoons using just Flow Cytometry based on our 2019 paper and can be found here: https://bio-protocol.org/e3527
The second protocol provides detailed step-by-step guidance for to carry out robust co-IP experiments, for example of the same protein with two different epitope tags and can be found here: https://bio-protocol.org/e3526
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